Lungs: inflammation of the lungs (pneumonitis) may cause new trouble breathing, cough, or chest pain.Ĭolon (gut): inflammation of the colon (colitis) can cause diarrhea or abdominal pain. Many rashes improve with creams, but sometimes they need more intense treatment.

More severe rashes can be painful and lead to blisters. Mild rashes can just be redness of the skin and/or itchiness. Skin: a faint rash is the most common skin irAE. Extreme fatigue may be a sign of a hormone problem. Tell your doctor about any of these adverse effects, even if mild:įatigue: usually mild and goes away on its own within 1 to 2 days. Most are mild or only seen on laboratory test results, but some can be severe and need treatment or hospitalization. Immune-related adverse events can occur almost anywhere in the body and at any time, even after you are finished with immunotherapy treatment.

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If there is too little of a particular hormone, the gland or organ it normally controls will not function correctly. Nonfunctioning tumors press on or damage the pituitary and prevent it from secreting enough hormones. Too much thyroid-stimulating hormone (TSH) may cause:

Extreme dislike of or concern about one or more parts of the body.

Snoring or pauses in breathing during sleep.

Tingling or numbness in the hands and fingers.

In children, excessive growth of the whole body.

In adults, growth of the bones in the face, hands, and feet.

Growth deceleration with weight gain in children.

Growth of fine hair on the face, upper back, or arms.

Thin skin that may include purple or pink stretch marks on the chest or abdomen.

Weight gain reflected in the face, neck, and trunk of the body, but thin arms and legs.

Too much adrenocorticotropic hormone (ACTH) may cause:

The flow of breast milk in a woman who is not pregnant or breastfeeding.

Less frequent or no menstrual periods or menstrual periods with a very light flow.

The symptoms of functioning pituitary tumors depend on the particular hormone the tumor is overproducing.

Adrenal hormone issue